Non sedating antihistamine drug list
Other common adverse effects in first-generation H-antihistamines include dizziness, tinnitus, blurred vision, euphoria, uncoordination, anxiety, increased appetite leading to weight gain, insomnia, tremor, nausea and vomiting, constipation, diarrhea, dry mouth, and dry cough.Infrequent adverse effects include urinary retention, palpitations, hypotension, headache, hallucination, and psychosis.-receptors and have a better tolerability profile compared to the first-generation agents.E-triprolidine, for example, is 1000-fold more potent than Z-triprolidine.This difference relates to the positioning and fit of the molecules in the histamine HThese compounds are structurally related to the ethylenediamines and the ethanolamines, and produce significant anticholinergic adverse effects.Compounds from this group are often used for motion sickness, vertigo, nausea, and vomiting.
They are effective in the relief of allergic symptoms, but are typically moderately to highly potent muscarinic acetylcholine receptor (anticholinergic) antagonists as well.Furthermore, essentially the same proportion of patients reported no benefit from either type of treatment."-receptor and their ability to cross the blood-brain barrier.The most common adverse effect is sedation; this "side-effect" is utilized in many OTC sleeping-aid preparations.There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions.